1. Tong L#, Zhao Q#, Datan E, Lin GQ, Minn I, Pomper MG, Yu B, Romo D, He QL*, Liu JO*. Triptolide: reflections on two decades of research and prospects for the future. Nat. Prod. Rep.2021,38(4),843-860(IF=12.002) |
2. Yi, X.#; Zhao, Q.#; Tian, Z.; Jia, X.; Cao, W.; Liu, W.* Insights into the Functionalization of the Methylsalicyclic Moiety during the Biosynthesis of Chlorothricin by Comparative Kinetic Assays of the Activities of Two KAS III‐like Acyltransferases. Chinese J. Chem.2019, 37(8),821-826 (IF=3.826) |
3. Chen, D.#; Zhao, Q.#; Liu, W.*, Discovery of caerulomycin/collismycin-type 2,2'-bipyridine natural products in the genomic era. J. Ind. Microbiol. Biot. 2019, 46:459-468 (IF=2.993) |
4. Wang, M.; Chen, D.; Zhao, Q.; Liu, W.*, Isolation, Structure Elucidation, and Biosynthesis of a CysteateContaining Non-ribosomal Peptide in Streptomyces lincolnensis. J. Org. Chem. 2018, 83(13): 7102-7108 (IF=4.745) |
5. Zhong, G.; Zhao, Q.; Zhang, Q.; Liu, W.*, 4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavage. Nat. Commun. 2017, 8, 16109 (IF=11.878) |
6. Chen, M.; Zhang, Y.; Du, Y.; Zhao, Q.; Zhang, Q.; Wu, J.; Liu, W.*, Enzymatic competition and cooperation branch the caerulomycin biosynthetic pathway toward different 2,2'-bipyridine members. Org. Biomol. Chem. 2017, 15(26): 5472-5475 (IF=3.49) |
7. Wang, M.; Zhao, Q.*; Zhang Q.; Liu, W.*, Differences in PLP-Dependent Cysteinyl Processing Lead to Diverse S‑Functionalization of Lincosamide Antibiotics. J. Am. Chem. Soc. 2016, 138, 6438-6351. (IF=14.695) |
8. Wang, M.#; Zhao, Q.#; Liu, W.*, The versatile low-molecular-weight thiols: Beyond cell protection. Bioessays 2015, 37(12): 1262-1267. (IF= 4.396) |
9. Zhao, Q.#; Wang, M.#; Xu, D.; Zhang, Q.; Liu, W.*, Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A. Nature 2015, 518, 115-119. (IF=43.07)(Featured in: Elusive source of sulfur unravelled. Nature 2015, 518, 45-46; Natl. Sci. Rev. 2015, 2, 382–384; F1000Prime 2015, doi: 10.3410/f.725320497.793503602 and doi: 10.3410/f.725320497.793503765) |
10. Sun, P.; Zhao Q.; Wu, Z.; Zhang, W.; Liu, W.*, 1,19-seco-Avermectin Analogues from a ΔaveCDE Mutant Streptomyces avermectinius Strain. J. Nat. Prod. 2015, 78, 301−305. (IF=4.257) |
11. Sun, P.; Zhao Q.; Zhang, H.; Wu, J.; Liu, W.*, Effect of Stereochemistry of Avermectin-Like 6,6-Spiroketals on Biological Activities and Endogenous Biotransformations in Streptomyces avermectinius. ChemBioChem 2014, 15(5), 660-664. (IF=2.593) |
12. Wang, J.; Zhang, F.; Pu, J.; Zhao, J.; Zhao, Q.; Tang, G.*, Characterization of AvaR1, an autoregulator receptor that negatively controls avermectins production in a high avermectin-producing strain. Biotechnol. Lett. 2014, 36(4), 813-819. (IF=2.154) |
13. Sun, P.;Zhao, Q.; Yu, F.; Zhang, H.; Wu, Z.; Wang, Y-Y.; Wang, Y.; Liu, W.*, Spiroketal formation and modification in avermectin biosynthesis involves a dual activity of AveC. J. Am. Chem. Soc. 2013, 135 (4), 1540-1548. (IF=14.695)(Hot off the press. Nat. Prod. Rep. 2013) |
14. Qu, X.; Pang, B.; Zhang, Z.; Chen, M.; Wu, Z.; Zhao, Q.; Zhang, Q.; Wang, Y.; Liu, Y.; Liu, W.*, Caerulomycins and Collismycins Share a Common Paradigm for 2, 2’-Bipyridine Biosynthesis via an Unusual Hybrid Polyketide-Peptide Assembly Logic. J. Am. Chem. Soc. 2012, 134 (22), 9038-9041. (IF=14.695) |
15. Zhao, Q.; He, Q.; Ding, W.; Tang, M.; Kang, Q.; Yu, Y.; Deng, W.; Zhang, Q.; Fang, J.; Tang, G., Liu W.*, Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis. Chem. Biol. 2008, 15(7), 693-705. (IF=5.915)(Featured in: Antibiotic biosynthesis: from Genes to Enzymes. Nat. China 2008, Doi: 10.1038/nchina.2008.196) |
16. Li, L.; Deng, W.; Song, J.; Ding, W.; Zhao, Q.; Peng, C.; Song, W.; Tang, G.; Liu, W.*, Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner. J. Bacteriol. 2008, 190 (1), 251-263. (IF=3.234) |
17. Shao, L.; Qu, X.; Jia, X.; Zhao, Q.; Tian, Z.; Wang, M.; Tang, G.; Liu, W.*, Cloning and characterization of a bacterial iterative type I polyketide synthase gene encoding the 6-methylsalicyclic acid synthase. Biochem. Bioph. Res. Com. 2006, 345 (1), 133-139. (IF=2.705) |
18. Jia, X.; Tian, Z.; Shao, L.; Qu, X.; Zhao, Q.; Tang, J.; Tang, G.; Liu, W.*, Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis. Chem. Biol. 2006, 13 (6), 575-585. (IF=5.915) |