| 姓名： | 吴晟 | 性别： | 男 |
| 职称： | 青年研究员 | 学历： | 博士研究生 |
| 专家类别： | 硕导 | 职务： | |
| 电话： | 传真： | ||
| 电子邮箱： | wusheng@shutcm.edu.cn | ||
| 通讯地址： | 上海市浦东新区蔡伦路1200号 | ||
| 个人主页： | |||
招生专业：
| 院系名称 | 专业大类 | 一级学科 | 专业代码/专业名称 | 学位类型 | 招生类型 |
| 创新中药研究院 | 理学 | 中药学 | 100800/中药学 | 学术型 | 硕士 |
个人简历：
| 2022-目前 | 青年研究员，硕导，上海中医药大学 创新中药研究院 |
| 2019-2022 | 博士后，加州大学河滨分校（导师：李嫣然 教授） |
| 2016-2019 | 中级工程师，上海市园林工程有限公司 |
| 2009-2015 | 硕博连读，中科院上海有机化学研究所（导师：唐功利研究员） |
| 2005-2009 | 本科，中南大学湘雅医学院，药学专业 |
研究内容：
药用植物来源的活性天然产物生物合成途径解析 |
| 利用合成生物学技术开展稀有中药天然产物的微生物创制工作 |
1. Wu, S., Zhou, A., Hiugano, K., Yoda, A., Xie, X., Yamane, K., Miura, K., Nomura, T.*, Li, Y.*, “Identification of a Prunus MAX1 homolog as a unique strigol synthase.” New Phytologist, 2023, 239(5), 1819-1833.
2. Xu, S.#,Wu, S. #, Li, Y.*, “Investigating plant biosynthetic pathways using heterologous gene expression: yeast as a heterologous host.” Engineering Natural Product Biosynthesis. Methods in Molecular Biology, 2022, vol 2489, pp 369-393, Humana, New York, NY. (An article in a book chapter)
3. Wu, S., Chang, L. J., Tian, L.*, “Identification and characterization of two regiospecific tricetin UDP-dependent glycosyltransferases from pomegranate (Punica granatum L.)” Plants, 2022, 11(6), 810.
4. Wu, S., Li, Y.*, “A unique sulfotransferase-involving strigolactone biosynthetic route in Sorghum.” Front. Plant Sci.2021, doi: 10.3389/fpls.2021.793459.
5. Wu, S.#, Ma, X.#, Zhou, A., Valenzuela, A., Zhou, K.*, Li, Y.*, Establishment of strigolactone-producing bacterium-yeast consortium. Sci. Adv.2021, 7(38): eabh4048.
6. Wu, S., Wilson, AE., Chang, L. J., Tian, L.*, “Exploring the phytochemical landscape of the early-diverging flowering plant Amborella trichopoda Baill.” Molecules2019, 24(21): 3814.
7. Jin, W. B.#, Wu, S. #, Jian, X. H., Yuan, H.*, Tang, G. L.*, “A radical S-adenosyl-L-methionine enzyme and a methyltransferase catalyze cyclopropane formation in natural product biosynthesis.”Nat Commun.2018,9(1): 2771.
8. Wu, S., Tian, L.*, “A new flavone glucoside together with known ellagitannins and flavones with anti-diabetic and anti-obesity activities from the flowers of pomegranate (Punica granatum).” Nat Prod Res.2019, 33: 252-257.
9. Wu, S., Tian, L.*, “Diverse phytochemicals and bioactivities in the ancient fruit and modern functional food pomegranate (Punica granatum).” Molecules.2017, 22: 1606.
10. Wu, S. # , Jian, X. H.#, Yuan, H.#, Jin, W. B., Yin, Y., Wang, L.Y., Zhao, J., Tang, G. L.*, “Unified biosynthetic origin of the benzodipyrrole subunits in CC-1065. ” ACS Chem. Biol., 2017, 12(6):1603-1610.
11. Zhou, A., Kane, A., Wu, S., Wang, K., Santiago, M., Ishiguro, Y., Yoneyama, K., Palayam, M., Shabek, N., Xie, X., Nelson. D, Li. Y., “Evolution of interorganismal strigolactone biosynthesis in seed plants.” Science.2025, 387(6731): eadp0779.